Major Shareholders

Since Cryo-Save Group N.V. is not incorporated in the UK, the rights of shareholders may be different from the rights of shareholders in a UK incorporated company.

The current number of securities in issue is 9,639,191, including 396,500 shares held in treasury, and the percentage of securities not in public hands is 37.92%.

Percentage holdings* of its major shareholders

• M. J. Waeterschoot 19.84%

• J. P. G. Goossens 18.08%

• Mineworkers Pension Scheme 5.4%

• British Coal Staff Superannuation Scheme 5.4%

*excluding shares held in treasury